| Prevention and Wellness |
| Overview | Behavioral Cardiology Lab | Duke Center for Living Complementary Approaches |
Complementary and Alternative Medical (CAM)
Practice in Cardiology
Faculty
Mitchell W. Krucoff, MD Director, CAM Research Laboratory
Suzanne W. Crater, ANP-C Coordinator, CAM Practitioners
Michael S. Cuffe, MD
Daniel B. Mark MD, MPH Director, Outcomes/EQOL
Kerry L. Lee, PhD Senior Biostatistician

Complementary and alternative medical practices
are widely used, but little systematic data exist on their mechanisms of
action, safety, or effectiveness. Patients with heart disease may realize
unique benefits or suffer life threatening complications from alternative
therapies, making well-designed clinical trials of their safety and efficacy
mandatory for optimal therapeutic
strategies.
A thorough understanding of the spectrum from biochemical
mechanisms of herbal remedies to intangible "noetic" medical
therapies with no known mechanism, such as healing touch, distant healing and
prayer, is an area of growing research activity and funding potential.
The CAM research
laboratory studies such therapies and their mechanisms of activity, clinical outcome,
impact on quality of life and cost-effectiveness in patients, including those with congestive
heart failure and ischemic heart disease. In 2005 the laboratory led the first multicenter,
prospective, randomized trial of distant intercessory prayer and bedside music,
imagery and touch therapy (MIT).
Other research examples include:
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Measures of physiologic response to biofield therapies
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An NIH-funded randomized study of chelation therapy
Study of the
biochemical mechanisms of herbal remedies
The laboratory offers cardiovascular medicine fellows the opportunity to gain mentoring and experience in CAM practices in cardiology settings through their exposure to and participation in such research.
Selected Publications
- Krucoff MW, Crater SW,
Gallup D, Blankenship JC, Cuffe M, Guarneri M, Krieger RA, Kshettry V,
Morris K, Oz M, Pichard A, Sketch Jr M, Koenig HG, Mark D, Lee KL. Music,
imagery, touch and prayer as adjuncts to interventional cardiac care: the
Monitoring and Actualization of Noetic TRAinings (MANTRA) II randomized
study. Lancet 2005;366:211-17
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Vogel JH, Bolling SF, Costello RB, Guarneri EM, Krucoff, MW, Longhurst JC, Olshansky B, Pelletier KR, Tracy CM, Vogel RA; Integrating Complementary Medicine Into Cardiovascular Medicine: A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. J Am Coll Cardiol 2005;46:184-221.
- Yager JE, Crater SW, Krucoff MW. "Prayer and Cardiovascular Disease" in press Complementary Clinical Medicine: The Clinical Handbook Oz M, Stein RA eds., Humana Press 2004.
- Krucoff MW, Liebowitz R, Vogel JH, Mark D. "Complementary and Alternative Medical Therapies: Opening the Door to the Science and Practice of Integrative Medicine in Cardiovascular Care" in press Hurst: The Heart, Logue RB, Schlant RC et al eds., McGraw Hill Publ 2004.
- Dusek JA, Astin JA, Hibberd PL, Krucoff MW. Healing prayer outcomes studies: consensus recommendations. Alt Therapies 2003; 9, No. 3, (suppl): A44-A53.




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